G10S (p.Gly10Ser) variant of MET (P08581)
G10S (p.Gly10Ser) in MET (P08581) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G10S (p.Gly10Ser) variant details
- p.Gly10Ser
- Ensembl rs2116578256
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.07
- MetaLR 0.47
- MetaSVM -0.17
- CADD 19.80
- PolyPhen-2 0.99
- SIFT 0.55
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available