E28E (p.Glu28Glu) variant of MET (P08581)
E28E (p.Glu28Glu) in MET (P08581) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
E28E (p.Glu28Glu) variant details
- p.Glu28Glu
- rs759602956
- gnomAD 7-116699168-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.328
- AlphaMissense 0.25
- MetaLR 0.52
- MetaSVM -0.08
- CADD 9.64
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available
- Literature evidence available