Y99H (p.Tyr99His) variant of MCM3 (P25205)
Y99H (p.Tyr99His) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
Y99H (p.Tyr99His) variant details
- p.Tyr99His
- gnomAD rs1318409377
- Missense
- Variant Prioritization Score for Impact Estimate 0.593
- CADD 23.20
- PolyPhen-2 0.01
- SIFT 0.25
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available