Y91C (p.Tyr91Cys) variant of MCM3 (P25205)
Y91C (p.Tyr91Cys) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data.
Y91C (p.Tyr91Cys) variant details
- p.Tyr91Cys
- gnomAD rs1259052165
- Missense
- Variant Prioritization Score for Impact Estimate 0.674
- CADD 29.70
- PolyPhen-2 0.95
- SIFT 0.09
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)