Y45H (p.Tyr45His) variant of MCM3 (P25205)
Y45H (p.Tyr45His) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data.
Y45H (p.Tyr45His) variant details
- p.Tyr45His
- TOPMed rs1327072696
- gnomAD rs1327072696
- Missense
- Variant Prioritization Score for Impact Estimate 0.366
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.42
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)