Y45C (p.Tyr45Cys) variant of MCM3 (P25205)
Y45C (p.Tyr45Cys) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data.
Y45C (p.Tyr45Cys) variant details
- p.Tyr45Cys
- TOPMed rs1766319171
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the REMAINING population (allele frequency 1.7e-05)