V127M (p.Val127Met) variant of MCM3 (P25205)
V127M (p.Val127Met) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
V127M (p.Val127Met) variant details
- p.Val127Met
- 1000Genomes rs573520418
- ExAC rs573520418
- TOPMed rs573520418
- gnomAD rs573520418
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- CADD 24.80
- PolyPhen-2 0.87
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available