V125G (p.Val125Gly) variant of MCM3 (P25205)
V125G (p.Val125Gly) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
V125G (p.Val125Gly) variant details
- p.Val125Gly
- ExAC rs764929595
- gnomAD rs764929595
- Missense
- Variant Prioritization Score for Impact Estimate 0.663
- CADD 28.80
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available