V100E (p.Val100Glu) variant of MCM3 (P25205)
V100E (p.Val100Glu) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
V100E (p.Val100Glu) variant details
- p.Val100Glu
- TOPMed rs921984322
- gnomAD rs921984322
- Missense
- Variant Prioritization Score for Impact Estimate 0.658
- CADD 28.60
- PolyPhen-2 0.70
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available