V100A (p.Val100Ala) variant of MCM3 (P25205)
V100A (p.Val100Ala) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
V100A (p.Val100Ala) variant details
- p.Val100Ala
- TOPMed rs921984322
- gnomAD rs921984322
- Missense
- Variant Prioritization Score for Impact Estimate 0.606
- CADD 24.60
- PolyPhen-2 0.20
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available