S122C (p.Ser122Cys) variant of MCM3 (P25205)
S122C (p.Ser122Cys) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
S122C (p.Ser122Cys) variant details
- p.Ser122Cys
- ExAC rs758234731
- gnomAD rs758234731
- Missense
- Variant Prioritization Score for Impact Estimate 0.649
- CADD 27.10
- PolyPhen-2 0.83
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available