S112Y (p.Ser112Tyr) variant of MCM3 (P25205)
S112Y (p.Ser112Tyr) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data.
S112Y (p.Ser112Tyr) variant details
- p.Ser112Tyr
- TOPMed rs1415108126
- gnomAD rs1415108126
- Missense
- Variant Prioritization Score for Impact Estimate 0.768
- CADD 25.30
- PolyPhen-2 0.71
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)