S108F (p.Ser108Phe) variant of MCM3 (P25205)
S108F (p.Ser108Phe) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data.
S108F (p.Ser108Phe) variant details
- p.Ser108Phe
- ExAC rs746375857
- gnomAD rs746375857
- Missense
- Variant Prioritization Score for Impact Estimate 0.767
- CADD 24.90
- PolyPhen-2 0.77
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 0.00048)