R55L (p.Arg55Leu) variant of MCM3 (P25205)
R55L (p.Arg55Leu) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data.
R55L (p.Arg55Leu) variant details
- p.Arg55Leu
- ExAC rs750663816
- TOPMed rs750663816
- gnomAD rs750663816
- Missense
- Variant Prioritization Score for Impact Estimate 0.829
- CADD 31.00
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)