R37L (p.Arg37Leu) variant of MCM3 (P25205)
R37L (p.Arg37Leu) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data.
R37L (p.Arg37Leu) variant details
- p.Arg37Leu
- ESP rs150433204
- TOPMed rs150433204
- gnomAD rs150433204
- Missense
- Variant Prioritization Score for Impact Estimate 0.639
- CADD 23.10
- PolyPhen-2 0.12
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 9e-07)