N43S (p.Asn43Ser) variant of MCM3 (P25205)
N43S (p.Asn43Ser) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data.
N43S (p.Asn43Ser) variant details
- p.Asn43Ser
- ExAC rs748860335
- gnomAD rs748860335
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- CADD 22.40
- PolyPhen-2 0.04
- SIFT 0.25
- Most common in the South Asian population (allele frequency 0.00021)