K140E (p.Lys140Glu) variant of MCM3 (P25205)
K140E (p.Lys140Glu) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data.
K140E (p.Lys140Glu) variant details
- p.Lys140Glu
- TOPMed rs900735602
- Missense
- Variant Prioritization Score for Impact Estimate 0.683
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)