I40M (p.Ile40Met) variant of MCM3 (P25205)
I40M (p.Ile40Met) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data.
I40M (p.Ile40Met) variant details
- p.Ile40Met
- gnomAD rs1766321355
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- CADD 18.10
- PolyPhen-2 0.39
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 3e-05)