G101R (p.Gly101Arg) variant of MCM3 (P25205)
G101R (p.Gly101Arg) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
G101R (p.Gly101Arg) variant details
- p.Gly101Arg
- TOPMed rs975283792
- gnomAD rs975283792
- Missense
- Variant Prioritization Score for Impact Estimate 0.803
- CADD 27.90
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available