G101A (p.Gly101Ala) variant of MCM3 (P25205)
G101A (p.Gly101Ala) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
G101A (p.Gly101Ala) variant details
- p.Gly101Ala
- ExAC rs764837213
- TOPMed rs764837213
- gnomAD rs764837213
- Missense
- Variant Prioritization Score for Impact Estimate 0.749
- CADD 23.20
- PolyPhen-2 0.32
- SIFT 0.47
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available