F70L (p.Phe70Leu) variant of MCM3 (P25205)
F70L (p.Phe70Leu) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
F70L (p.Phe70Leu) variant details
- p.Phe70Leu
- TOPMed rs1177768756
- Missense
- Variant Prioritization Score for Impact Estimate 0.592
- CADD 23.50
- PolyPhen-2 0.02
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available