F22L (p.Phe22Leu) variant of MCM3 (P25205)
F22L (p.Phe22Leu) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data.
F22L (p.Phe22Leu) variant details
- p.Phe22Leu
- ExAC rs771235249
- gnomAD rs771235249
- Missense
- Variant Prioritization Score for Impact Estimate 0.696
- CADD 33.00
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9.9e-06)