E59K (p.Glu59Lys) variant of MCM3 (P25205)
E59K (p.Glu59Lys) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data.
E59K (p.Glu59Lys) variant details
- p.Glu59Lys
- TOPMed rs1475520607
- gnomAD rs1475520607
- Missense
- Variant Prioritization Score for Impact Estimate 0.737
- CADD 22.90
- PolyPhen-2 0.11
- SIFT 0.74
- Most common in the Middle Eastern population (allele frequency 0.00017)