E11D (p.Glu11Asp) variant of MCM3 (P25205)
E11D (p.Glu11Asp) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data.
E11D (p.Glu11Asp) variant details
- p.Glu11Asp
- gnomAD rs1443436101
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- CADD 21.00
- PolyPhen-2 0.04
- SIFT 0.36
- Most common in the Latino/Admixed American population (allele frequency 0.00011)