D88Y (p.Asp88Tyr) variant of MCM3 (P25205)
D88Y (p.Asp88Tyr) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data.
D88Y (p.Asp88Tyr) variant details
- p.Asp88Tyr
- ExAC rs767489375
- gnomAD rs767489375
- Missense
- Variant Prioritization Score for Impact Estimate 0.779
- CADD 25.00
- PolyPhen-2 0.98
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 9e-07)