D24E (p.Asp24Glu) variant of MCM3 (P25205)
D24E (p.Asp24Glu) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data.
D24E (p.Asp24Glu) variant details
- p.Asp24Glu
- ExAC rs773409479
- gnomAD rs773409479
- Missense
- Variant Prioritization Score for Impact Estimate 0.601
- CADD 22.50
- PolyPhen-2 0.85
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)