C134F (p.Cys134Phe) variant of MCM3 (P25205)
C134F (p.Cys134Phe) in MCM3 (P25205) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.84 / 1. The record also includes population frequency data.
C134F (p.Cys134Phe) variant details
- p.Cys134Phe
- TOPMed rs1323593904
- gnomAD rs1323593904
- Missense
- Variant Prioritization Score for Impact Estimate 0.844
- CADD 33.00
- PolyPhen-2 0.86
- SIFT 0.00
- Most common in the HGDP:MOZABITE population (allele frequency 0.02)