W77L (p.Trp77Leu) variant of MBP (Myelin basic protein)
W77L (p.Trp77Leu) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
W77L (p.Trp77Leu) variant details
- p.Trp77Leu
- rs1310155270
- gnomAD 18-76980009-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- CADD 5.26
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available
- Literature evidence available