W77* (p.Trp77Ter) variant of MBP (Myelin basic protein)
W77* (p.Trp77Ter) in MBP (Myelin basic protein) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, published literature, and structural context.
W77* (p.Trp77Ter) variant details
- p.Trp77Ter
- rs1479671372
- gnomAD 18-76980008-C-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.107
- CADD 5.83
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available
- Literature evidence available