S67Y (p.Ser67Tyr) variant of MBP (Myelin basic protein)
S67Y (p.Ser67Tyr) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
S67Y (p.Ser67Tyr) variant details
- p.Ser67Tyr
- ExAC rs776127568
- gnomAD rs776127568
- Missense
- Variant Prioritization Score for Impact Estimate 0.464
- REVEL 0.24
- CADD 26.20
- PolyPhen-2 0.82
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available