S16G (p.Ser16Gly) variant of MBP (Myelin basic protein)
S16G (p.Ser16Gly) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
S16G (p.Ser16Gly) variant details
- p.Ser16Gly
- TOPMed rs1599254873
- Missense
- Variant Prioritization Score for Impact Estimate 0.111
- REVEL 0.12
- CADD 7.06
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available