R37P (p.Arg37Pro) variant of MBP (Myelin basic protein)
R37P (p.Arg37Pro) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
R37P (p.Arg37Pro) variant details
- p.Arg37Pro
- ESP rs145675270
- ExAC rs145675270
- TOPMed rs145675270
- gnomAD rs145675270
- Missense
- Variant Prioritization Score for Impact Estimate 0.118
- REVEL 0.17
- CADD 0.16
- PolyPhen-2 0.10
- SIFT 0.09
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available