R23G (p.Arg23Gly) variant of MBP (Myelin basic protein)
R23G (p.Arg23Gly) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
R23G (p.Arg23Gly) variant details
- p.Arg23Gly
- TOPMed rs1408415487
- Missense
- Variant Prioritization Score for Impact Estimate 0.0759
- REVEL 0.03
- CADD 10.60
- PolyPhen-2 0.00
- SIFT 0.26
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available