P89A (p.Pro89Ala) variant of MBP (Myelin basic protein)
P89A (p.Pro89Ala) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
P89A (p.Pro89Ala) variant details
- p.Pro89Ala
- ExAC rs765907364
- TOPMed rs765907364
- gnomAD rs765907364
- Missense
- Variant Prioritization Score for Impact Estimate 0.613
- REVEL 0.50
- CADD 25.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available