P85S (p.Pro85Ser) variant of MBP (Myelin basic protein)
P85S (p.Pro85Ser) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P85S (p.Pro85Ser) variant details
- p.Pro85Ser
- TOPMed rs1971695481
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.04
- CADD 21.20
- PolyPhen-2 0.05
- SIFT 0.06
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available