P85L (p.Pro85Leu) variant of MBP (Myelin basic protein)
P85L (p.Pro85Leu) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
P85L (p.Pro85Leu) variant details
- p.Pro85Leu
- cosmic curated COSV10467
- Missense
- Variant Prioritization Score for Impact Estimate 0.292
- REVEL 0.12
- CADD 25.10
- PolyPhen-2 0.21
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available