N11K (p.Asn11Lys) variant of MBP (Myelin basic protein)
N11K (p.Asn11Lys) in MBP (Myelin basic protein) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.04 / 1. The record also includes population frequency data and structural context.
N11K (p.Asn11Lys) variant details
- p.Asn11Lys
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0405
- REVEL 0.01
- CADD 0.00
- PolyPhen-2 0.01
- SIFT 0.93
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available