K14T (p.Lys14Thr) variant of MBP (Myelin basic protein)
K14T (p.Lys14Thr) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
K14T (p.Lys14Thr) variant details
- p.Lys14Thr
- TOPMed rs959367050
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- REVEL 0.14
- CADD 22.50
- PolyPhen-2 0.98
- SIFT 0.10
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available