I92M (p.Ile92Met) variant of MBP (Myelin basic protein)
I92M (p.Ile92Met) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
I92M (p.Ile92Met) variant details
- p.Ile92Met
- gnomAD rs1228024634
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.12
- CADD 25.10
- PolyPhen-2 0.29
- SIFT 0.00
- Most common in the HGDP:FRENCH population (allele frequency 0.019)
- Structural context available