H90R (p.His90Arg) variant of MBP (Myelin basic protein)
H90R (p.His90Arg) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
H90R (p.His90Arg) variant details
- p.His90Arg
- gnomAD rs1007140529
- Missense
- Variant Prioritization Score for Impact Estimate 0.433
- REVEL 0.30
- CADD 25.00
- PolyPhen-2 0.25
- SIFT 0.00
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available