H90P (p.His90Pro) variant of MBP (Myelin basic protein)
H90P (p.His90Pro) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
H90P (p.His90Pro) variant details
- p.His90Pro
- gnomAD rs1007140529
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.29
- CADD 26.30
- PolyPhen-2 0.69
- SIFT 0.00
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available