G86R (p.Gly86Arg) variant of MBP (Myelin basic protein)
G86R (p.Gly86Arg) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
G86R (p.Gly86Arg) variant details
- p.Gly86Arg
- ExAC rs754642326
- gnomAD rs754642326
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.16
- CADD 14.30
- PolyPhen-2 0.01
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available