G24E (p.Gly24Glu) variant of MBP (Myelin basic protein)
G24E (p.Gly24Glu) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
G24E (p.Gly24Glu) variant details
- p.Gly24Glu
- TOPMed rs1401525409
- gnomAD rs1401525409
- Missense
- Variant Prioritization Score for Impact Estimate 0.31
- REVEL 0.25
- CADD 17.10
- PolyPhen-2 1.00
- SIFT 0.51
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available