F46= variant of MBP (Myelin basic protein)
F46= in MBP (Myelin basic protein) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; low impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
F46= variant details
- rs377221551
- NCI-TCGA Cosmic COSV1005
- Variant assessed as somatic; low impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- AlphaMissense 0.97
- MetaLR 0.21
- MetaSVM -0.61
- PolyPhen-2 0.98
- SIFT 0.01
- MutPred 0.26
- UniProt: Variant assessed as somatic; low impact.
- Population evidence available
- Structural context available