D84N (p.Asp84Asn) variant of MBP (Myelin basic protein)
D84N (p.Asp84Asn) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
D84N (p.Asp84Asn) variant details
- p.Asp84Asn
- ExAC rs764803706
- TOPMed rs764803706
- gnomAD rs764803706
- Missense
- Variant Prioritization Score for Impact Estimate 0.441
- REVEL 0.19
- CADD 26.80
- PolyPhen-2 0.64
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available