A15T (p.Ala15Thr) variant of MBP (Myelin basic protein)
A15T (p.Ala15Thr) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
A15T (p.Ala15Thr) variant details
- p.Ala15Thr
- Ensembl rs202054986
- Missense
- Variant Prioritization Score for Impact Estimate 0.17
- REVEL 0.07
- CADD 5.48
- PolyPhen-2 0.01
- SIFT 0.42
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available