A15D (p.Ala15Asp) variant of MBP (Myelin basic protein)
A15D (p.Ala15Asp) in MBP (Myelin basic protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
A15D (p.Ala15Asp) variant details
- p.Ala15Asp
- ExAC rs750008587
- gnomAD rs750008587
- Missense
- Variant Prioritization Score for Impact Estimate 0.145
- REVEL 0.03
- CADD 8.37
- PolyPhen-2 0.02
- SIFT 0.41
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available