Y60C (p.Tyr60Cys) variant of MAPK3 (P27361)
Y60C (p.Tyr60Cys) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
Y60C (p.Tyr60Cys) variant details
- p.Tyr60Cys
- cosmic curated COSV10808
- 1000Genomes rs147961867
- ESP rs147961867
- ExAC rs147961867
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.13
- CADD 23.40
- PolyPhen-2 0.02
- SIFT 0.09
- Most common in the 1KG:JPT population (allele frequency 0.0049)
- Structural context available