Y53C (p.Tyr53Cys) variant of MAPK3 (P27361)
Y53C (p.Tyr53Cys) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
Y53C (p.Tyr53Cys) variant details
- p.Tyr53Cys
- cosmic curated COSV99531
- Ensembl rs2151048638
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.27
- CADD 27.60
- PolyPhen-2 0.69
- SIFT 0.05
- Population evidence available
- Structural context available