Y42C (p.Tyr42Cys) variant of MAPK3 (P27361)
Y42C (p.Tyr42Cys) in MAPK3 (P27361) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
Y42C (p.Tyr42Cys) variant details
- p.Tyr42Cys
- ExAC rs752945713
- gnomAD rs752945713
- Missense
- Variant Prioritization Score for Impact Estimate 0.595
- REVEL 0.62
- CADD 29.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available